Greedy Insider
AMLX Insider Trades and Greediness Scores
Amylyx Pharmaceuticals, Inc. (AMLX) insider trades: since Dec 1, 2025, Greedy Insider recorded 2 open-market buys and 31 sales on Form 4 from 7 insiders. The strongest recent filing scored 88 (Strong).
Who bought and who sold
Across the last 33 scoreable Form 4 transactions in AMLX, 2 were open-market purchases and 31 were sales. The table lists the most recent filings with each one's Greediness Score, so the structurally unusual trades are easy to spot first.
| Insider | Role | Type | Shares | Date | Score | ||
|---|---|---|---|---|---|---|---|
| MILNE GEORGE M JR | Director | Sell | 30000.0 | 830904.0 | 2026-10-05 | 67 | View |
| Mazzariello Gina | Chief Legal Officer | Sell | 9525.0 | 309139.6 | 2026-09-10 | 86 | View |
| Mazzariello Gina | Chief Legal Officer | Sell | 11.0 | 366.74 | 2026-09-10 | 71 | View |
| Cohen Joshua B | CEO | Sell | 29545.0 | 950040.2 | 2026-09-10 | 85 | View |
| Cohen Joshua B | CEO | Sell | 919.0 | 30463.748 | 2026-09-10 | 71 | View |
| Bedrosian Camille L | Chief Medical Officer | Sell | 7947.0 | 256003.86 | 2026-09-10 | 86 | View |
| Bedrosian Camille L | Chief Medical Officer | Sell | 2081.0 | 68864.24 | 2026-09-10 | 76 | View |
| FRATES JAMES M | CFO | Sell | 9768.0 | 315194.8 | 2026-09-10 | 88 | View |
| FRATES JAMES M | CFO | Sell | 1042.0 | 34625.867 | 2026-09-10 | 72 | View |
| Klee Justin B. | CEO | Sell | 29025.0 | 932552.94 | 2026-09-10 | 85 | View |
The strongest recent filing
FRATES JAMES M (CFO) sold 9,768 shares of Amylyx Pharmaceuticals, Inc. on Sep 10, 2026, a filing that scored 88 (Strong). It scored Strong because a senior insider was trading and it was direct personal ownership. The score describes the filing, not future returns. This is not investment advice.
Cluster activity
A cluster buy is present: 5 insiders (Mazzariello Gina, Cohen Joshua B, Bedrosian Camille L, FRATES JAMES M) traded AMLX the same direction within a 7-day window. Shared conviction is a stronger structural signal than a lone trade.
How this compares with Amylyx Pharmaceuticals, Inc.'s own history
Open-market buys make up 6% of the 33 scoreable AMLX transactions on record between Dec 1, 2025 and Oct 5, 2026. Comparing a filing with the company's own buy/sell mix is how you tell a routine disposal from an unusual accumulation.
Methodology and sources
Scores come from six published, user-adjustable factors (insider role, cluster activity, trade size versus the insider's own history, position impact, filing urgency, and direct versus indirect ownership). The score describes the filing, not future returns. This is not investment advice.
Key facts
- Scoreable Form 4 transactions on record: 33
- Open-market buys: 2
- Sales: 31
- Distinct insiders: 7
- Strongest recent Greediness Score: 88 (Strong)
Primary sources
Related
- Strongest filing
- AMLX in the live feed
- How the Greediness Score works
- What is a cluster buy?
- Form 4 transaction codes
The score describes the filing, not future returns. This is not investment advice.