Greedy Insider
SYRE Insider Trades and Greediness Scores
Spyre Therapeutics, Inc. (SYRE) insider trades: since Dec 1, 2025, Greedy Insider recorded 0 open-market buys and 94 sales on Form 4 from 7 insiders. The strongest recent filing scored 89 (Strong).
Who bought and who sold
Across the last 94 scoreable Form 4 transactions in SYRE, 0 were open-market purchases and 94 were sales. The table lists the most recent filings with each one's Greediness Score, so the structurally unusual trades are easy to spot first.
| Insider | Role | Type | Shares | Date | Score | ||
|---|---|---|---|---|---|---|---|
| Turtle Cameron | CEO | Sell | 4990.0 | 465916.3 | 2026-10-01 | 81 | View |
| Burrows Scott L | CFO | Sell | 600.0 | 53442.0 | 2026-10-01 | 67 | View |
| Burrows Scott L | CFO | Sell | 3071.0 | 285449.44 | 2026-10-01 | 75 | View |
| King-Jones Heidy | See Remarks | Sell | 2100.0 | 194670.0 | 2026-10-01 | 57 | View |
| Burrows Scott L | CFO | Sell | 229.0 | 21427.53 | 2026-10-01 | 67 | View |
| King-Jones Heidy | See Remarks | Sell | 400.0 | 35696.0 | 2026-10-01 | 54 | View |
| Burrows Scott L | CFO | Sell | 1500.0 | 135405.0 | 2026-10-01 | 70 | View |
| Burrows Scott L | CFO | Sell | 2100.0 | 193032.0 | 2026-10-01 | 72 | View |
| King-Jones Heidy | See Remarks | Sell | 2600.0 | 242996.0 | 2026-10-01 | 59 | View |
| Turtle Cameron | CEO | Sell | 600.0 | 53484.0 | 2026-10-01 | 67 | View |
The strongest recent filing
Burrows Scott L (CFO) sold 10,000 shares of Spyre Therapeutics, Inc. on Jun 25, 2026, a filing that scored 89 (Strong). It scored Strong because a senior insider was trading and it was direct personal ownership. The score describes the filing, not future returns. This is not investment advice.
Cluster activity
A cluster buy is present: 5 insiders (Burrows Scott L, Sloan Sheldon, Turtle Cameron, Fairmount Funds Management LLC) traded SYRE the same direction within a 7-day window. Shared conviction is a stronger structural signal than a lone trade.
How this compares with Spyre Therapeutics, Inc.'s own history
Open-market buys make up 0% of the 94 scoreable SYRE transactions on record between Dec 1, 2025 and Oct 1, 2026. Comparing a filing with the company's own buy/sell mix is how you tell a routine disposal from an unusual accumulation.
Methodology and sources
Scores come from six published, user-adjustable factors (insider role, cluster activity, trade size versus the insider's own history, position impact, filing urgency, and direct versus indirect ownership). The score describes the filing, not future returns. This is not investment advice.
Key facts
- Scoreable Form 4 transactions on record: 94
- Open-market buys: 0
- Sales: 94
- Distinct insiders: 7
- Strongest recent Greediness Score: 89 (Strong)
Primary sources
Related
- Strongest filing
- SYRE in the live feed
- How the Greediness Score works
- What is a cluster buy?
- Form 4 transaction codes
The score describes the filing, not future returns. This is not investment advice.